Exploratory Data Analysis (EDA)

Overview of the data

Summary

• Elimination profile appears to be bi-exponential
• Body weight and gender appear to influence PK

Data

finaldat <- read.csv(file='./data/finaldat.csv')
DT::datatable(finaldat, rownames = FALSE, filter = "top", 
          options = list(pageLength = 5, scrollX = TRUE))

Demographics Table

dm_table <- readRDS(file='./tables/dmtable.RDS')
dm_table

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## 7  BLACK <NA>           36 (24%)
## 8  OTHER <NA>           33 (22%)
## 9  WHITE <NA>           60 (40%)
## 10    WT  150       71 (55 - 94)
## 
## $content
## $content
## $data
##       label         n             stat_0       
##  [1,] data.frame,19 data.frame,19 data.frame,19
##  [2,] data.frame,19 data.frame,19 data.frame,19
##  [3,] data.frame,19 data.frame,19 data.frame,19
##  [4,] data.frame,19 data.frame,19 data.frame,19
##  [5,] data.frame,19 data.frame,19 data.frame,19
##  [6,] data.frame,19 data.frame,19 data.frame,19
##  [7,] data.frame,19 data.frame,19 data.frame,19
##  [8,] data.frame,19 data.frame,19 data.frame,19
##  [9,] data.frame,19 data.frame,19 data.frame,19
## [10,] data.frame,19 data.frame,19 data.frame,19
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [[1]]
##   txt font.size italic bold underlined color shading.color font.family
## 1            NA     NA   NA         NA  <NA>          <NA>        <NA>
##   hansi.family eastasia.family cs.family vertical.align width height  url
## 1         <NA>            <NA>      <NA>           <NA>    NA     NA <NA>
##   eq_data word_field_data img_data seq_index
## 1    <NA>            <NA>     NULL         1
## 
## attr(,"class")
## [1] "paragraph"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "chunkset_struct"
## 
## $col_keys
## [1] "label"  "n"      "stat_0"
## 
## $colwidths
##     label         n    stat_0 
## 1.3042010 0.5400883 1.4572026 
## 
## $rowheights
##  [1] 0.4285635 0.3982765 0.4285635 0.4285635 0.3982765 0.4285635 0.4285635
##  [8] 0.4285635 0.4285635 0.4285635
## 
## $hrule
##  [1] "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto"
## 
## $spans
## $spans$rows
##       [,1] [,2] [,3]
##  [1,]    1    1    1
##  [2,]    1    1    1
##  [3,]    1    1    1
##  [4,]    1    1    1
##  [5,]    1    1    1
##  [6,]    1    1    1
##  [7,]    1    1    1
##  [8,]    1    1    1
##  [9,]    1    1    1
## [10,]    1    1    1
## 
## $spans$columns
##       [,1] [,2] [,3]
##  [1,]    1    1    1
##  [2,]    1    1    1
##  [3,]    1    1    1
##  [4,]    1    1    1
##  [5,]    1    1    1
##  [6,]    1    1    1
##  [7,]    1    1    1
##  [8,]    1    1    1
##  [9,]    1    1    1
## [10,]    1    1    1
## 
## 
## $styles
## $styles$cells
## $vertical.align
## $data
##       label n     stat_0
##  [1,] "top" "top" "top" 
##  [2,] "top" "top" "top" 
##  [3,] "top" "top" "top" 
##  [4,] "top" "top" "top" 
##  [5,] "top" "top" "top" 
##  [6,] "top" "top" "top" 
##  [7,] "top" "top" "top" 
##  [8,] "top" "top" "top" 
##  [9,] "top" "top" "top" 
## [10,] "top" "top" "top" 
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "center"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $width
## $data
##       label  n stat_0
##  [1,]    NA NA     NA
##  [2,]    NA NA     NA
##  [3,]    NA NA     NA
##  [4,]    NA NA     NA
##  [5,]    NA NA     NA
##  [6,]    NA NA     NA
##  [7,]    NA NA     NA
##  [8,]    NA NA     NA
##  [9,]    NA NA     NA
## [10,]    NA NA     NA
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $height
## $data
##       label  n stat_0
##  [1,]    NA NA     NA
##  [2,]    NA NA     NA
##  [3,]    NA NA     NA
##  [4,]    NA NA     NA
##  [5,]    NA NA     NA
##  [6,]    NA NA     NA
##  [7,]    NA NA     NA
##  [8,]    NA NA     NA
##  [9,]    NA NA     NA
## [10,]    NA NA     NA
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.bottom
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
##  [6,]     0 0      0
##  [7,]     0 0      0
##  [8,]     0 0      0
##  [9,]     0 0      0
## [10,]     0 0      0
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.top
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
##  [6,]     0 0      0
##  [7,]     0 0      0
##  [8,]     0 0      0
##  [9,]     0 0      0
## [10,]     0 0      0
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.left
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
##  [6,]     0 0      0
##  [7,]     0 0      0
##  [8,]     0 0      0
##  [9,]     0 0      0
## [10,]     0 0      0
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.right
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
##  [6,]     0 0      0
##  [7,]     0 0      0
##  [8,]     0 0      0
##  [9,]     0 0      0
## [10,]     0 0      0
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.bottom
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
##  [6,]     0 0      0
##  [7,]     0 0      0
##  [8,]     0 0      0
##  [9,]     0 0      0
## [10,]     1 1      1
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.top
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
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## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.left
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
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## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.right
## $data
##       label n stat_0
##  [1,]     0 0      0
##  [2,]     0 0      0
##  [3,]     0 0      0
##  [4,]     0 0      0
##  [5,]     0 0      0
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## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.bottom
## $data
##       label   n       stat_0 
##  [1,] "black" "black" "black"
##  [2,] "black" "black" "black"
##  [3,] "black" "black" "black"
##  [4,] "black" "black" "black"
##  [5,] "black" "black" "black"
##  [6,] "black" "black" "black"
##  [7,] "black" "black" "black"
##  [8,] "black" "black" "black"
##  [9,] "black" "black" "black"
## [10,] "black" "black" "black"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.top
## $data
##       label   n       stat_0 
##  [1,] "black" "black" "black"
##  [2,] "black" "black" "black"
##  [3,] "black" "black" "black"
##  [4,] "black" "black" "black"
##  [5,] "black" "black" "black"
##  [6,] "black" "black" "black"
##  [7,] "black" "black" "black"
##  [8,] "black" "black" "black"
##  [9,] "black" "black" "black"
## [10,] "black" "black" "black"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.left
## $data
##       label   n       stat_0 
##  [1,] "black" "black" "black"
##  [2,] "black" "black" "black"
##  [3,] "black" "black" "black"
##  [4,] "black" "black" "black"
##  [5,] "black" "black" "black"
##  [6,] "black" "black" "black"
##  [7,] "black" "black" "black"
##  [8,] "black" "black" "black"
##  [9,] "black" "black" "black"
## [10,] "black" "black" "black"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.right
## $data
##       label   n       stat_0 
##  [1,] "black" "black" "black"
##  [2,] "black" "black" "black"
##  [3,] "black" "black" "black"
##  [4,] "black" "black" "black"
##  [5,] "black" "black" "black"
##  [6,] "black" "black" "black"
##  [7,] "black" "black" "black"
##  [8,] "black" "black" "black"
##  [9,] "black" "black" "black"
## [10,] "black" "black" "black"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.bottom
## $data
##       label   n       stat_0 
##  [1,] "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid"
## [10,] "solid" "solid" "solid"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.top
## $data
##       label   n       stat_0 
##  [1,] "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid"
## [10,] "solid" "solid" "solid"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.left
## $data
##       label   n       stat_0 
##  [1,] "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid"
## [10,] "solid" "solid" "solid"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.right
## $data
##       label   n       stat_0 
##  [1,] "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid"
## [10,] "solid" "solid" "solid"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $text.direction
## $data
##       label  n      stat_0
##  [1,] "lrtb" "lrtb" "lrtb"
##  [2,] "lrtb" "lrtb" "lrtb"
##  [3,] "lrtb" "lrtb" "lrtb"
##  [4,] "lrtb" "lrtb" "lrtb"
##  [5,] "lrtb" "lrtb" "lrtb"
##  [6,] "lrtb" "lrtb" "lrtb"
##  [7,] "lrtb" "lrtb" "lrtb"
##  [8,] "lrtb" "lrtb" "lrtb"
##  [9,] "lrtb" "lrtb" "lrtb"
## [10,] "lrtb" "lrtb" "lrtb"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "lrtb"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $background.color
## $data
##       label         n             stat_0       
##  [1,] "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent"
##  [5,] "transparent" "transparent" "transparent"
##  [6,] "transparent" "transparent" "transparent"
##  [7,] "transparent" "transparent" "transparent"
##  [8,] "transparent" "transparent" "transparent"
##  [9,] "transparent" "transparent" "transparent"
## [10,] "transparent" "transparent" "transparent"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hrule
## $data
##       label  n      stat_0
##  [1,] "auto" "auto" "auto"
##  [2,] "auto" "auto" "auto"
##  [3,] "auto" "auto" "auto"
##  [4,] "auto" "auto" "auto"
##  [5,] "auto" "auto" "auto"
##  [6,] "auto" "auto" "auto"
##  [7,] "auto" "auto" "auto"
##  [8,] "auto" "auto" "auto"
##  [9,] "auto" "auto" "auto"
## [10,] "auto" "auto" "auto"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "auto"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "cell_struct"
## 
## $styles$pars
## $text.align
## $data
##       label  n        stat_0  
##  [1,] "left" "center" "center"
##  [2,] "left" "center" "center"
##  [3,] "left" "center" "center"
##  [4,] "left" "center" "center"
##  [5,] "left" "center" "center"
##  [6,] "left" "center" "center"
##  [7,] "left" "center" "center"
##  [8,] "left" "center" "center"
##  [9,] "left" "center" "center"
## [10,] "left" "center" "center"
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] "left"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.bottom
## $data
##       label n stat_0
##  [1,]     5 5      5
##  [2,]     5 5      5
##  [3,]     5 5      5
##  [4,]     5 5      5
##  [5,]     5 5      5
##  [6,]     5 5      5
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## [10,]     5 5      5
## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.top
## $data
##       label n stat_0
##  [1,]     5 5      5
##  [2,]     5 5      5
##  [3,]     5 5      5
##  [4,]     5 5      5
##  [5,]     5 5      5
##  [6,]     5 5      5
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## 
## $keys
## [1] "label"  "n"      "stat_0"
## 
## $nrow
## [1] 10
## 
## $ncol
## [1] 3
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.left
## $data
##       label n stat_0
##  [1,]     5 5      5
##  [2,]     5 5      5
##  [3,]    15 5      5
##  [4,]    15 5      5
##  [5,]     5 5      5
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## [1] "fpstruct"
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##       label   n       stat_0 
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## attr(,"class")
## [1] "fpstruct"
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## $border.color.left
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##       label   n       stat_0 
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##  [3,] "black" "black" "black"
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## [1] "fpstruct"
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## $border.color.right
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##       label   n       stat_0 
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## [1] "black"
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## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.bottom
## $data
##       label   n       stat_0 
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## [1] "fpstruct"
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## $data
##       label   n       stat_0 
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## attr(,"class")
## [1] "fpstruct"
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## $border.style.left
## $data
##       label   n       stat_0 
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## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.right
## $data
##       label   n       stat_0 
##  [1,] "solid" "solid" "solid"
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## attr(,"class")
## [1] "fpstruct"
## 
## $shading.color
## $data
##       label         n             stat_0       
##  [1,] "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent"
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##  [6,] "transparent" "transparent" "transparent"
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## [1] 10
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## [1] "transparent"
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## attr(,"class")
## [1] "fpstruct"
## 
## $keep_with_next
## $data
##       label     n stat_0
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## [1] 10
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## $default
## [1] FALSE
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## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "par_struct"
## 
## $styles$text
## $color
## $data
##       label   n       stat_0 
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## [1] "black"
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## attr(,"class")
## [1] "fpstruct"
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## $font.size
## $data
##       label  n stat_0
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## [1] 10
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## [1] 11
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## attr(,"class")
## [1] "fpstruct"
## 
## $bold
## $data
##       label     n stat_0
##  [1,] FALSE FALSE  FALSE
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## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $italic
## $data
##       label     n stat_0
##  [1,] FALSE FALSE  FALSE
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## [1] 10
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## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $underlined
## $data
##       label     n stat_0
##  [1,] FALSE FALSE  FALSE
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## [1] 10
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## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $font.family
## $data
##       label   n       stat_0 
##  [1,] "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial"
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## [1] "label"  "n"      "stat_0"
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## [1] 10
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## [1] 3
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## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hansi.family
## $data
##       label   n       stat_0 
##  [1,] "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial"
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## [1] "label"  "n"      "stat_0"
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## [1] 10
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## [1] 3
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## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $eastasia.family
## $data
##       label   n       stat_0 
##  [1,] "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial"
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## [1] "label"  "n"      "stat_0"
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## [1] 10
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## [1] 3
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## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $cs.family
## $data
##       label   n       stat_0 
##  [1,] "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial"
##  [7,] "Arial" "Arial" "Arial"
##  [8,] "Arial" "Arial" "Arial"
##  [9,] "Arial" "Arial" "Arial"
## [10,] "Arial" "Arial" "Arial"
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## [1] "label"  "n"      "stat_0"
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## [1] 10
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## $ncol
## [1] 3
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## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $vertical.align
## $data
##       label      n          stat_0    
##  [1,] "baseline" "baseline" "baseline"
##  [2,] "baseline" "baseline" "baseline"
##  [3,] "baseline" "baseline" "baseline"
##  [4,] "baseline" "baseline" "baseline"
##  [5,] "baseline" "baseline" "baseline"
##  [6,] "baseline" "baseline" "baseline"
##  [7,] "baseline" "baseline" "baseline"
##  [8,] "baseline" "baseline" "baseline"
##  [9,] "baseline" "baseline" "baseline"
## [10,] "baseline" "baseline" "baseline"
## 
## $keys
## [1] "label"  "n"      "stat_0"
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## $nrow
## [1] 10
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## [1] 3
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## $default
## [1] "baseline"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $shading.color
## $data
##       label         n             stat_0       
##  [1,] "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent"
##  [5,] "transparent" "transparent" "transparent"
##  [6,] "transparent" "transparent" "transparent"
##  [7,] "transparent" "transparent" "transparent"
##  [8,] "transparent" "transparent" "transparent"
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## [1] "label"  "n"      "stat_0"
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## [1] 10
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## $ncol
## [1] 3
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## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "text_struct"
## 
## 
## attr(,"class")
## [1] "complex_tabpart"
## 
## $footer
## $dataset
##   label n stat_0
## 1     1 1      1
## 
## $content
## $content
## $data
##      label         n             stat_0       
## [1,] data.frame,19 data.frame,19 data.frame,19
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## $keys
## [1] "label"  "n"      "stat_0"
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## $nrow
## [1] 1
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## $ncol
## [1] 3
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## $default
## [[1]]
##   txt font.size italic bold underlined color shading.color font.family
## 1            NA     NA   NA         NA  <NA>          <NA>        <NA>
##   hansi.family eastasia.family cs.family vertical.align width height  url
## 1         <NA>            <NA>      <NA>           <NA>    NA     NA <NA>
##   eq_data word_field_data img_data seq_index
## 1    <NA>            <NA>     NULL         1
## 
## attr(,"class")
## [1] "paragraph"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "chunkset_struct"
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Mean Concentration

mean_conctable <- readRDS(file='./tables/mean_conctable.RDS')
mean_conctable

## $header
## $dataset
##   TIME       5000      10000      20000
## 1      Dose Group Dose Group Dose Group
## 2 TIME       5000      10000      20000
## 
## $content
## $content
## $data
##      TIME          5000          10000         20000        
## [1,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
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##      TIME    5000    10000   20000  
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## [1] "fpstruct"
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## $border.style.right
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##      TIME    5000    10000   20000  
## [1,] "solid" "solid" "solid" "solid"
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## [1] "fpstruct"
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##      TIME   5000   10000  20000 
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## attr(,"class")
## [1] "fpstruct"
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##      TIME          5000          10000         20000        
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## [1] "fpstruct"
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##      TIME   5000   10000  20000 
## [1,] "auto" "auto" "auto" "auto"
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## attr(,"class")
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## attr(,"class")
## [1] "cell_struct"
## 
## $styles$pars
## $text.align
## $data
##      TIME     5000     10000    20000   
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## $padding.bottom
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##      TIME 5000 10000 20000
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##      TIME 5000 10000 20000
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## [1] "fpstruct"
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##      TIME 5000 10000 20000
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##      TIME 5000 10000 20000
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##      TIME 5000 10000 20000
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## 
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## attr(,"class")
## [1] "fpstruct"
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## $border.width.top
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##      TIME 5000 10000 20000
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## $keys
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## $nrow
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## attr(,"class")
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## $border.width.left
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## attr(,"class")
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## $border.width.right
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##      TIME    5000    10000   20000  
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##      TIME    5000    10000   20000  
## [1,] "black" "black" "black" "black"
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## [1] "fpstruct"
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## $border.style.bottom
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##      TIME    5000    10000   20000  
## [1,] "solid" "solid" "solid" "solid"
## [2,] "solid" "solid" "solid" "solid"
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## [1] "TIME"  "5000"  "10000" "20000"
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## [1] "fpstruct"
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##      TIME    5000    10000   20000  
## [1,] "solid" "solid" "solid" "solid"
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##      TIME    5000    10000   20000  
## [1,] "solid" "solid" "solid" "solid"
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## [1] "TIME"  "5000"  "10000" "20000"
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## attr(,"class")
## [1] "fpstruct"
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## $border.style.right
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##      TIME    5000    10000   20000  
## [1,] "solid" "solid" "solid" "solid"
## [2,] "solid" "solid" "solid" "solid"
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## [1] "TIME"  "5000"  "10000" "20000"
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## [1] "fpstruct"
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##      TIME          5000          10000         20000        
## [1,] "transparent" "transparent" "transparent" "transparent"
## [2,] "transparent" "transparent" "transparent" "transparent"
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## [1] "fpstruct"
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## [1,] FALSE FALSE FALSE FALSE
## [2,] FALSE FALSE FALSE FALSE
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## [1] FALSE
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## [1] "fpstruct"
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## [1] "par_struct"
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##      TIME 5000 10000 20000
## [1,]   11   11    11    11
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## attr(,"class")
## [1] "fpstruct"
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## $bold
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##      TIME 5000 10000 20000
## [1,] TRUE TRUE  TRUE  TRUE
## [2,] TRUE TRUE  TRUE  TRUE
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## $nrow
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## $italic
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##       TIME  5000 10000 20000
## [1,] FALSE FALSE FALSE FALSE
## [2,] FALSE FALSE FALSE FALSE
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## attr(,"class")
## [1] "fpstruct"
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## [1,] FALSE FALSE FALSE FALSE
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## [1] "fpstruct"
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## $font.family
## $data
##      TIME    5000    10000   20000  
## [1,] "Arial" "Arial" "Arial" "Arial"
## [2,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hansi.family
## $data
##      TIME    5000    10000   20000  
## [1,] "Arial" "Arial" "Arial" "Arial"
## [2,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $eastasia.family
## $data
##      TIME    5000    10000   20000  
## [1,] "Arial" "Arial" "Arial" "Arial"
## [2,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $cs.family
## $data
##      TIME    5000    10000   20000  
## [1,] "Arial" "Arial" "Arial" "Arial"
## [2,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $vertical.align
## $data
##      TIME       5000       10000      20000     
## [1,] "baseline" "baseline" "baseline" "baseline"
## [2,] "baseline" "baseline" "baseline" "baseline"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "baseline"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $shading.color
## $data
##      TIME          5000          10000         20000        
## [1,] "transparent" "transparent" "transparent" "transparent"
## [2,] "transparent" "transparent" "transparent" "transparent"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 2
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "text_struct"
## 
## 
## attr(,"class")
## [1] "complex_tabpart"
## 
## $body
## $dataset
##     TIME              5000           10000           20000
## 1   0.00           0 (0-0)         0 (0-0)         0 (0-0)
## 2   0.25  19.5 (5.19-56.4) 38.8 (4.77-111) 58.3 (6.83-164)
## 3   0.50  32.6 (9.88-84.3)   64.9 (19-167) 96.9 (27.9-247)
## 4   1.00   48.1 (17.2-119) 96.3 (30.6-235)  144 (41.1-349)
## 5   2.00   56.2 (17.7-116)  112 (32.7-236)  169 (51.7-352)
## 6   3.00   55.8 (19.8-118)  112 (37.7-235)    167 (56-348)
## 7   4.00   51.7 (15.4-131)  103 (27.5-264)  155 (37.8-400)
## 8   6.00  41.2 (9.77-91.4) 82.4 (14.3-182)  124 (21.9-270)
## 9   8.00    34.7 (9.36-67) 69.9 (21.7-136)  104 (29.8-199)
## 10 12.00    25 (2.98-69.8) 49.6 (5.06-140) 75.8 (8.52-208)
## 11 16.00  18.7 (1.08-57.5)    37.5 (0-115)    56.8 (0-169)
## 12 24.00 9.52 (0.103-32.9)   19.3 (0-67.3)   28.1 (0-99.8)
## 
## $content
## $content
## $data
##       TIME          5000          10000         20000        
##  [1,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [2,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [3,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [4,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [5,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [6,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [7,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [8,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
##  [9,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
## [10,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
## [11,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
## [12,] data.frame,19 data.frame,19 data.frame,19 data.frame,19
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [[1]]
##   txt font.size italic bold underlined color shading.color font.family
## 1            NA     NA   NA         NA  <NA>          <NA>        <NA>
##   hansi.family eastasia.family cs.family vertical.align width height  url
## 1         <NA>            <NA>      <NA>           <NA>    NA     NA <NA>
##   eq_data word_field_data img_data seq_index
## 1    <NA>            <NA>     NULL         1
## 
## attr(,"class")
## [1] "paragraph"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "chunkset_struct"
## 
## $col_keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $colwidths
## [1] 1.5 1.5 1.5 1.5
## 
## $rowheights
##  [1] 0.25 0.25 0.25 0.25 0.25 0.25 0.25 0.25 0.25 0.25 0.25 0.25
## 
## $hrule
##  [1] "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto" "auto"
## [11] "auto" "auto"
## 
## $spans
## $spans$rows
##       [,1] [,2] [,3] [,4]
##  [1,]    1    1    1    1
##  [2,]    1    1    1    1
##  [3,]    1    1    1    1
##  [4,]    1    1    1    1
##  [5,]    1    1    1    1
##  [6,]    1    1    1    1
##  [7,]    1    1    1    1
##  [8,]    1    1    1    1
##  [9,]    1    1    1    1
## [10,]    1    1    1    1
## [11,]    1    1    1    1
## [12,]    1    1    1    1
## 
## $spans$columns
##       [,1] [,2] [,3] [,4]
##  [1,]    1    1    1    1
##  [2,]    1    1    1    1
##  [3,]    1    1    1    1
##  [4,]    1    1    1    1
##  [5,]    1    1    1    1
##  [6,]    1    1    1    1
##  [7,]    1    1    1    1
##  [8,]    1    1    1    1
##  [9,]    1    1    1    1
## [10,]    1    1    1    1
## [11,]    1    1    1    1
## [12,]    1    1    1    1
## 
## 
## $styles
## $styles$cells
## $vertical.align
## $data
##       TIME     5000     10000    20000   
##  [1,] "center" "center" "center" "center"
##  [2,] "center" "center" "center" "center"
##  [3,] "center" "center" "center" "center"
##  [4,] "center" "center" "center" "center"
##  [5,] "center" "center" "center" "center"
##  [6,] "center" "center" "center" "center"
##  [7,] "center" "center" "center" "center"
##  [8,] "center" "center" "center" "center"
##  [9,] "center" "center" "center" "center"
## [10,] "center" "center" "center" "center"
## [11,] "center" "center" "center" "center"
## [12,] "center" "center" "center" "center"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "center"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $width
## $data
##       TIME 5000 10000 20000
##  [1,]   NA   NA    NA    NA
##  [2,]   NA   NA    NA    NA
##  [3,]   NA   NA    NA    NA
##  [4,]   NA   NA    NA    NA
##  [5,]   NA   NA    NA    NA
##  [6,]   NA   NA    NA    NA
##  [7,]   NA   NA    NA    NA
##  [8,]   NA   NA    NA    NA
##  [9,]   NA   NA    NA    NA
## [10,]   NA   NA    NA    NA
## [11,]   NA   NA    NA    NA
## [12,]   NA   NA    NA    NA
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $height
## $data
##       TIME 5000 10000 20000
##  [1,]   NA   NA    NA    NA
##  [2,]   NA   NA    NA    NA
##  [3,]   NA   NA    NA    NA
##  [4,]   NA   NA    NA    NA
##  [5,]   NA   NA    NA    NA
##  [6,]   NA   NA    NA    NA
##  [7,]   NA   NA    NA    NA
##  [8,]   NA   NA    NA    NA
##  [9,]   NA   NA    NA    NA
## [10,]   NA   NA    NA    NA
## [11,]   NA   NA    NA    NA
## [12,]   NA   NA    NA    NA
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.bottom
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.top
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.left
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.right
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.bottom
## $data
##       TIME 5000 10000 20000
##  [1,]  0.0  0.0   0.0   0.0
##  [2,]  0.0  0.0   0.0   0.0
##  [3,]  0.0  0.0   0.0   0.0
##  [4,]  0.0  0.0   0.0   0.0
##  [5,]  0.0  0.0   0.0   0.0
##  [6,]  0.0  0.0   0.0   0.0
##  [7,]  0.0  0.0   0.0   0.0
##  [8,]  0.0  0.0   0.0   0.0
##  [9,]  0.0  0.0   0.0   0.0
## [10,]  0.0  0.0   0.0   0.0
## [11,]  0.0  0.0   0.0   0.0
## [12,]  1.5  1.5   1.5   1.5
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.top
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.left
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.right
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.bottom
## $data
##       TIME      5000      10000     20000    
##  [1,] "black"   "black"   "black"   "black"  
##  [2,] "black"   "black"   "black"   "black"  
##  [3,] "black"   "black"   "black"   "black"  
##  [4,] "black"   "black"   "black"   "black"  
##  [5,] "black"   "black"   "black"   "black"  
##  [6,] "black"   "black"   "black"   "black"  
##  [7,] "black"   "black"   "black"   "black"  
##  [8,] "black"   "black"   "black"   "black"  
##  [9,] "black"   "black"   "black"   "black"  
## [10,] "black"   "black"   "black"   "black"  
## [11,] "black"   "black"   "black"   "black"  
## [12,] "#666666" "#666666" "#666666" "#666666"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.top
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.left
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.right
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.bottom
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.top
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.left
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.right
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $text.direction
## $data
##       TIME   5000   10000  20000 
##  [1,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [2,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [3,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [4,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [5,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [6,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [7,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [8,] "lrtb" "lrtb" "lrtb" "lrtb"
##  [9,] "lrtb" "lrtb" "lrtb" "lrtb"
## [10,] "lrtb" "lrtb" "lrtb" "lrtb"
## [11,] "lrtb" "lrtb" "lrtb" "lrtb"
## [12,] "lrtb" "lrtb" "lrtb" "lrtb"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "lrtb"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $background.color
## $data
##       TIME          5000          10000         20000        
##  [1,] "transparent" "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent" "transparent"
##  [5,] "transparent" "transparent" "transparent" "transparent"
##  [6,] "transparent" "transparent" "transparent" "transparent"
##  [7,] "transparent" "transparent" "transparent" "transparent"
##  [8,] "transparent" "transparent" "transparent" "transparent"
##  [9,] "transparent" "transparent" "transparent" "transparent"
## [10,] "transparent" "transparent" "transparent" "transparent"
## [11,] "transparent" "transparent" "transparent" "transparent"
## [12,] "transparent" "transparent" "transparent" "transparent"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hrule
## $data
##       TIME   5000   10000  20000 
##  [1,] "auto" "auto" "auto" "auto"
##  [2,] "auto" "auto" "auto" "auto"
##  [3,] "auto" "auto" "auto" "auto"
##  [4,] "auto" "auto" "auto" "auto"
##  [5,] "auto" "auto" "auto" "auto"
##  [6,] "auto" "auto" "auto" "auto"
##  [7,] "auto" "auto" "auto" "auto"
##  [8,] "auto" "auto" "auto" "auto"
##  [9,] "auto" "auto" "auto" "auto"
## [10,] "auto" "auto" "auto" "auto"
## [11,] "auto" "auto" "auto" "auto"
## [12,] "auto" "auto" "auto" "auto"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "auto"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "cell_struct"
## 
## $styles$pars
## $text.align
## $data
##       TIME     5000     10000    20000   
##  [1,] "center" "center" "center" "center"
##  [2,] "center" "center" "center" "center"
##  [3,] "center" "center" "center" "center"
##  [4,] "center" "center" "center" "center"
##  [5,] "center" "center" "center" "center"
##  [6,] "center" "center" "center" "center"
##  [7,] "center" "center" "center" "center"
##  [8,] "center" "center" "center" "center"
##  [9,] "center" "center" "center" "center"
## [10,] "center" "center" "center" "center"
## [11,] "center" "center" "center" "center"
## [12,] "center" "center" "center" "center"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "left"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.bottom
## $data
##       TIME 5000 10000 20000
##  [1,]    5    5     5     5
##  [2,]    5    5     5     5
##  [3,]    5    5     5     5
##  [4,]    5    5     5     5
##  [5,]    5    5     5     5
##  [6,]    5    5     5     5
##  [7,]    5    5     5     5
##  [8,]    5    5     5     5
##  [9,]    5    5     5     5
## [10,]    5    5     5     5
## [11,]    5    5     5     5
## [12,]    5    5     5     5
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.top
## $data
##       TIME 5000 10000 20000
##  [1,]    5    5     5     5
##  [2,]    5    5     5     5
##  [3,]    5    5     5     5
##  [4,]    5    5     5     5
##  [5,]    5    5     5     5
##  [6,]    5    5     5     5
##  [7,]    5    5     5     5
##  [8,]    5    5     5     5
##  [9,]    5    5     5     5
## [10,]    5    5     5     5
## [11,]    5    5     5     5
## [12,]    5    5     5     5
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.left
## $data
##       TIME 5000 10000 20000
##  [1,]    5    5     5     5
##  [2,]    5    5     5     5
##  [3,]    5    5     5     5
##  [4,]    5    5     5     5
##  [5,]    5    5     5     5
##  [6,]    5    5     5     5
##  [7,]    5    5     5     5
##  [8,]    5    5     5     5
##  [9,]    5    5     5     5
## [10,]    5    5     5     5
## [11,]    5    5     5     5
## [12,]    5    5     5     5
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $padding.right
## $data
##       TIME 5000 10000 20000
##  [1,]    5    5     5     5
##  [2,]    5    5     5     5
##  [3,]    5    5     5     5
##  [4,]    5    5     5     5
##  [5,]    5    5     5     5
##  [6,]    5    5     5     5
##  [7,]    5    5     5     5
##  [8,]    5    5     5     5
##  [9,]    5    5     5     5
## [10,]    5    5     5     5
## [11,]    5    5     5     5
## [12,]    5    5     5     5
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 5
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $line_spacing
## $data
##       TIME 5000 10000 20000
##  [1,]    1    1     1     1
##  [2,]    1    1     1     1
##  [3,]    1    1     1     1
##  [4,]    1    1     1     1
##  [5,]    1    1     1     1
##  [6,]    1    1     1     1
##  [7,]    1    1     1     1
##  [8,]    1    1     1     1
##  [9,]    1    1     1     1
## [10,]    1    1     1     1
## [11,]    1    1     1     1
## [12,]    1    1     1     1
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 1
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.bottom
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.top
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.left
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.right
## $data
##       TIME 5000 10000 20000
##  [1,]    0    0     0     0
##  [2,]    0    0     0     0
##  [3,]    0    0     0     0
##  [4,]    0    0     0     0
##  [5,]    0    0     0     0
##  [6,]    0    0     0     0
##  [7,]    0    0     0     0
##  [8,]    0    0     0     0
##  [9,]    0    0     0     0
## [10,]    0    0     0     0
## [11,]    0    0     0     0
## [12,]    0    0     0     0
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.bottom
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "black"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.top
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "black"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.left
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "black"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.right
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "black"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.bottom
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.top
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.left
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.right
## $data
##       TIME    5000    10000   20000  
##  [1,] "solid" "solid" "solid" "solid"
##  [2,] "solid" "solid" "solid" "solid"
##  [3,] "solid" "solid" "solid" "solid"
##  [4,] "solid" "solid" "solid" "solid"
##  [5,] "solid" "solid" "solid" "solid"
##  [6,] "solid" "solid" "solid" "solid"
##  [7,] "solid" "solid" "solid" "solid"
##  [8,] "solid" "solid" "solid" "solid"
##  [9,] "solid" "solid" "solid" "solid"
## [10,] "solid" "solid" "solid" "solid"
## [11,] "solid" "solid" "solid" "solid"
## [12,] "solid" "solid" "solid" "solid"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $shading.color
## $data
##       TIME          5000          10000         20000        
##  [1,] "transparent" "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent" "transparent"
##  [5,] "transparent" "transparent" "transparent" "transparent"
##  [6,] "transparent" "transparent" "transparent" "transparent"
##  [7,] "transparent" "transparent" "transparent" "transparent"
##  [8,] "transparent" "transparent" "transparent" "transparent"
##  [9,] "transparent" "transparent" "transparent" "transparent"
## [10,] "transparent" "transparent" "transparent" "transparent"
## [11,] "transparent" "transparent" "transparent" "transparent"
## [12,] "transparent" "transparent" "transparent" "transparent"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $keep_with_next
## $data
##        TIME  5000 10000 20000
##  [1,] FALSE FALSE FALSE FALSE
##  [2,] FALSE FALSE FALSE FALSE
##  [3,] FALSE FALSE FALSE FALSE
##  [4,] FALSE FALSE FALSE FALSE
##  [5,] FALSE FALSE FALSE FALSE
##  [6,] FALSE FALSE FALSE FALSE
##  [7,] FALSE FALSE FALSE FALSE
##  [8,] FALSE FALSE FALSE FALSE
##  [9,] FALSE FALSE FALSE FALSE
## [10,] FALSE FALSE FALSE FALSE
## [11,] FALSE FALSE FALSE FALSE
## [12,] FALSE FALSE FALSE FALSE
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "par_struct"
## 
## $styles$text
## $color
## $data
##       TIME    5000    10000   20000  
##  [1,] "black" "black" "black" "black"
##  [2,] "black" "black" "black" "black"
##  [3,] "black" "black" "black" "black"
##  [4,] "black" "black" "black" "black"
##  [5,] "black" "black" "black" "black"
##  [6,] "black" "black" "black" "black"
##  [7,] "black" "black" "black" "black"
##  [8,] "black" "black" "black" "black"
##  [9,] "black" "black" "black" "black"
## [10,] "black" "black" "black" "black"
## [11,] "black" "black" "black" "black"
## [12,] "black" "black" "black" "black"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "black"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $font.size
## $data
##       TIME 5000 10000 20000
##  [1,]   11   11    11    11
##  [2,]   11   11    11    11
##  [3,]   11   11    11    11
##  [4,]   11   11    11    11
##  [5,]   11   11    11    11
##  [6,]   11   11    11    11
##  [7,]   11   11    11    11
##  [8,]   11   11    11    11
##  [9,]   11   11    11    11
## [10,]   11   11    11    11
## [11,]   11   11    11    11
## [12,]   11   11    11    11
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] 11
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $bold
## $data
##        TIME  5000 10000 20000
##  [1,] FALSE FALSE FALSE FALSE
##  [2,] FALSE FALSE FALSE FALSE
##  [3,] FALSE FALSE FALSE FALSE
##  [4,] FALSE FALSE FALSE FALSE
##  [5,] FALSE FALSE FALSE FALSE
##  [6,] FALSE FALSE FALSE FALSE
##  [7,] FALSE FALSE FALSE FALSE
##  [8,] FALSE FALSE FALSE FALSE
##  [9,] FALSE FALSE FALSE FALSE
## [10,] FALSE FALSE FALSE FALSE
## [11,] FALSE FALSE FALSE FALSE
## [12,] FALSE FALSE FALSE FALSE
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $italic
## $data
##        TIME  5000 10000 20000
##  [1,] FALSE FALSE FALSE FALSE
##  [2,] FALSE FALSE FALSE FALSE
##  [3,] FALSE FALSE FALSE FALSE
##  [4,] FALSE FALSE FALSE FALSE
##  [5,] FALSE FALSE FALSE FALSE
##  [6,] FALSE FALSE FALSE FALSE
##  [7,] FALSE FALSE FALSE FALSE
##  [8,] FALSE FALSE FALSE FALSE
##  [9,] FALSE FALSE FALSE FALSE
## [10,] FALSE FALSE FALSE FALSE
## [11,] FALSE FALSE FALSE FALSE
## [12,] FALSE FALSE FALSE FALSE
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $underlined
## $data
##        TIME  5000 10000 20000
##  [1,] FALSE FALSE FALSE FALSE
##  [2,] FALSE FALSE FALSE FALSE
##  [3,] FALSE FALSE FALSE FALSE
##  [4,] FALSE FALSE FALSE FALSE
##  [5,] FALSE FALSE FALSE FALSE
##  [6,] FALSE FALSE FALSE FALSE
##  [7,] FALSE FALSE FALSE FALSE
##  [8,] FALSE FALSE FALSE FALSE
##  [9,] FALSE FALSE FALSE FALSE
## [10,] FALSE FALSE FALSE FALSE
## [11,] FALSE FALSE FALSE FALSE
## [12,] FALSE FALSE FALSE FALSE
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] FALSE
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $font.family
## $data
##       TIME    5000    10000   20000  
##  [1,] "Arial" "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial" "Arial"
##  [7,] "Arial" "Arial" "Arial" "Arial"
##  [8,] "Arial" "Arial" "Arial" "Arial"
##  [9,] "Arial" "Arial" "Arial" "Arial"
## [10,] "Arial" "Arial" "Arial" "Arial"
## [11,] "Arial" "Arial" "Arial" "Arial"
## [12,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hansi.family
## $data
##       TIME    5000    10000   20000  
##  [1,] "Arial" "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial" "Arial"
##  [7,] "Arial" "Arial" "Arial" "Arial"
##  [8,] "Arial" "Arial" "Arial" "Arial"
##  [9,] "Arial" "Arial" "Arial" "Arial"
## [10,] "Arial" "Arial" "Arial" "Arial"
## [11,] "Arial" "Arial" "Arial" "Arial"
## [12,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $eastasia.family
## $data
##       TIME    5000    10000   20000  
##  [1,] "Arial" "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial" "Arial"
##  [7,] "Arial" "Arial" "Arial" "Arial"
##  [8,] "Arial" "Arial" "Arial" "Arial"
##  [9,] "Arial" "Arial" "Arial" "Arial"
## [10,] "Arial" "Arial" "Arial" "Arial"
## [11,] "Arial" "Arial" "Arial" "Arial"
## [12,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $cs.family
## $data
##       TIME    5000    10000   20000  
##  [1,] "Arial" "Arial" "Arial" "Arial"
##  [2,] "Arial" "Arial" "Arial" "Arial"
##  [3,] "Arial" "Arial" "Arial" "Arial"
##  [4,] "Arial" "Arial" "Arial" "Arial"
##  [5,] "Arial" "Arial" "Arial" "Arial"
##  [6,] "Arial" "Arial" "Arial" "Arial"
##  [7,] "Arial" "Arial" "Arial" "Arial"
##  [8,] "Arial" "Arial" "Arial" "Arial"
##  [9,] "Arial" "Arial" "Arial" "Arial"
## [10,] "Arial" "Arial" "Arial" "Arial"
## [11,] "Arial" "Arial" "Arial" "Arial"
## [12,] "Arial" "Arial" "Arial" "Arial"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "Arial"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $vertical.align
## $data
##       TIME       5000       10000      20000     
##  [1,] "baseline" "baseline" "baseline" "baseline"
##  [2,] "baseline" "baseline" "baseline" "baseline"
##  [3,] "baseline" "baseline" "baseline" "baseline"
##  [4,] "baseline" "baseline" "baseline" "baseline"
##  [5,] "baseline" "baseline" "baseline" "baseline"
##  [6,] "baseline" "baseline" "baseline" "baseline"
##  [7,] "baseline" "baseline" "baseline" "baseline"
##  [8,] "baseline" "baseline" "baseline" "baseline"
##  [9,] "baseline" "baseline" "baseline" "baseline"
## [10,] "baseline" "baseline" "baseline" "baseline"
## [11,] "baseline" "baseline" "baseline" "baseline"
## [12,] "baseline" "baseline" "baseline" "baseline"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "baseline"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $shading.color
## $data
##       TIME          5000          10000         20000        
##  [1,] "transparent" "transparent" "transparent" "transparent"
##  [2,] "transparent" "transparent" "transparent" "transparent"
##  [3,] "transparent" "transparent" "transparent" "transparent"
##  [4,] "transparent" "transparent" "transparent" "transparent"
##  [5,] "transparent" "transparent" "transparent" "transparent"
##  [6,] "transparent" "transparent" "transparent" "transparent"
##  [7,] "transparent" "transparent" "transparent" "transparent"
##  [8,] "transparent" "transparent" "transparent" "transparent"
##  [9,] "transparent" "transparent" "transparent" "transparent"
## [10,] "transparent" "transparent" "transparent" "transparent"
## [11,] "transparent" "transparent" "transparent" "transparent"
## [12,] "transparent" "transparent" "transparent" "transparent"
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 12
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "text_struct"
## 
## 
## attr(,"class")
## [1] "complex_tabpart"
## 
## $footer
## $dataset
## [1] TIME  5000  10000 20000
## <0 rows> (or 0-length row.names)
## 
## $content
## $content
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [[1]]
##   txt font.size italic bold underlined color shading.color font.family
## 1            NA     NA   NA         NA  <NA>          <NA>        <NA>
##   hansi.family eastasia.family cs.family vertical.align width height  url
## 1         <NA>            <NA>      <NA>           <NA>    NA     NA <NA>
##   eq_data word_field_data img_data seq_index
## 1    <NA>            <NA>     NULL         1
## 
## attr(,"class")
## [1] "paragraph"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## attr(,"class")
## [1] "chunkset_struct"
## 
## $col_keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $colwidths
## [1] 1.5 1.5 1.5 1.5
## 
## $rowheights
## numeric(0)
## 
## $hrule
## character(0)
## 
## $spans
## $spans$rows
##      [,1] [,2] [,3] [,4]
## 
## $spans$columns
##      [,1] [,2] [,3] [,4]
## 
## 
## $styles
## $styles$cells
## $vertical.align
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "center"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $width
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $height
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] NA
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.bottom
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.top
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.left
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $margin.right
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.bottom
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.top
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.left
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.width.right
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] 0
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.bottom
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.top
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.left
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.color.right
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.bottom
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.top
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.left
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $border.style.right
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "solid"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $text.direction
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "lrtb"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $background.color
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
## 
## $nrow
## [1] 0
## 
## $ncol
## [1] 4
## 
## $default
## [1] "transparent"
## 
## attr(,"class")
## [1] "fpstruct"
## 
## $hrule
## $data
##      TIME 5000 10000 20000
## 
## $keys
## [1] "TIME"  "5000"  "10000" "20000"
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Time Concentration by Subject

• Disposition appears bi-exponential

time_conc <- readRDS(file='./plots/time_concentration_by_subject.RDS')
time_conc

time_conc <- readRDS(file='./plots/time_concentration_by_subject.RDS')
time_conc |>
  plotly::ggplotly()

Facet Dose Group

• Possible gender difference in PK with observed concentrations higher in females

time_conc_dose_grp <- readRDS(file='./plots/time_concentration_facet_dose_group.RDS')
time_conc_dose_grp

time_conc_dose_grp <- readRDS(file='./plots/time_concentration_facet_dose_group.RDS')
time_conc_dose_grp |> 
  plotly::ggplotly()

Facet WT Linear

• Possible WT influence on PK with higher concentrations in lower body weight subjects

time_conc_wt <- readRDS(file='./plots/time_concentration_by_subject_by_wt_cut.RDS')
time_conc_wt

time_conc_wt <- readRDS(file='./plots/time_concentration_by_subject_by_wt_cut.RDS')
time_conc_wt |> 
  plotly::ggplotly()